Which test would you like to explore?

Trio-Smart
Three-Gas Breath Test
for SIBO, IMO, ISO

TrioSmartBreath.com

IBS-Smart
At-Home Blood Test
for PI-IBS

IBSSmart.com
Gemelli - Where to Start
Primary Gut
Symptom
Associated Conditions Associated Gas
or Antibodies
Suggested Gemelli
At-Home Tests
Bloating
SIBO IMO ISO
Hydrogen
Trio-Smart
PI-IBS
IBS-Smart
Diarrhea
ISO SIBO
Hydrogen Sulfide
Trio-Smart
PI-IBS
Anti-CdtB Anti-Vinculin
IBS-Smart
Constipation
IMO SIBO
Methane
Trio-Smart
Mixed
(Alternating Diarrhea & Constipation)
SIBO IMO ISO
Hydrogen Sulfide Methane
Trio-Smart
PI-IBS
Anti-CdtB Anti-Vinculin
IBS-Smart
Gemelli - Where to Start

Bloating

  • Associated Conditions:
    • SIBO
    • IMO
    • ISO
    • PI-IBS
  • Associated Gas or Antibodies:
    • Hydrogen
  • Suggested Gemelli At-Home Tests:
    • Trio-Smart
    • IBS-Smart

Diarrhea

  • Associated Conditions:
    • ISO
    • SIBO
    • PI-IBS
  • Associated Gas or Antibodies:
    • Hydrogen
    • Anti-CdtB
    • Anti-Vinculin
  • Suggested Gemelli At-Home Tests:
    • IBS-Smart

Constipation

  • Associated Conditions:
    • IMO
    • SIBO
  • Associated Gas or Antibodies:
    • Methane
  • Suggested Gemelli At-Home Tests:
    • Trio-Smart

Suggested Gemelli At-Home Tests

  • Associated Conditions:
    • SIBO
    • IMO
    • ISO
    • PI-IBS
  • Associated Gas or Antibodies:
    • Hydrogen Sulfide
    • Methane
    • Anti-CdtB
    • Anti-Vinculin
  • Suggested Gemelli At-Home Tests:
    • IBS-Smart

At-Home
Gut Health Tests
for
SIBO, IBS & More

Clinically-validated, pricision diagnostics delivered to your inbox.

Developed in Partnership with the MAST Program at Cedars-Sinai

Medically Associated Science and Technology (MAST) LogoCedars-Sinai logo

Struggling with Bloating, Abdominal Pain, Diarrhea, or Constipation?

We offer clinically certified, simple, at-home tests to help you identify the root cause of your gut symptoms so you can get on the treatment path right for you.

  • SIBO - Small Intestinal Bacterial Overgrowth
  • IMO - Intestinal Methanogen Overgrowth
  • ISO - Intestinal Sulfide Overproduction
  • PI-IBS - Post-Infectious Irritable Bowel Syndrome

No Lab Visits.
No Appointments.
Just Answers.

Snippets of diagnostic results from Gemelli gut tests.

Trusted by top GI clinics and teaching universities.

Leading clinics and hospitals choose our at-home GI diagnostic tests for reliable results.

The Only 3-Gas Breath Test for Identifying All 3 Types of SIBO

Trio-Smart breath test, collection bag, and mouthpiece with results displayed on a smartphone.

Learn more at:

TrioSmartBreath.com

Trio-Smart

The Only 3-Gas Breath Test for Identifying All 3 Types of SIBO

Trio-Smart

Trio-Smart is the ONLY breath test that measures all three fermented gases in your gut including hydrogen, methane, and hydrogen sulfide. Results are delivered directly to you.

  • Helps identify SIBO, IMO & ISO
  • 20x more sensitive than conventional breath tests
  • Clinically validated
  • At-home convenience
  • Trusted by over 100,000 patients & physicians

"Many patients could avoid years of frustration and hefty medical costs with one timely breath test."  —Dr. Mark Pimentel

The At-Home Test for Post-Infectious IBS (PI-IBS)

The At-Home Test for Post-Infectious IBS (PI-IBS)

IBS-Smart kit with Tasso device for blood collection

Learn more at:

IBSSmart.com

IBS-Smart

Many people do not know that IBS can develop as a result of food poisoning. Research shows that up to 11% of patients who experience a food-borne illness will develop post-infectious IBS. Some patients do not recall the food poisoning event and often wonder why they are having gut symptoms now.​

IBS-Smart is the only at-home capillary blood test that measures the 2 antibodies for PI-IBS: anti-CdtB and anti-vinculin.

  • Positive predictive value of 96% to 100%
  • No office or lab visit required
  • Simple and easy to use
  • At-home convenience
  • Fast results within 2-5 business days.

"I'm just very thankful for it because I am starting to feel better for the first time in over five years." —Sarah

How It Works in Three Easy Steps

1 - Order

Order your at-home sample collection kit online.

IBS-Smart and Trio-Smart kits with results displayed on a phone.

2 - Collect

Collect your samples at home and ship them back to the lab with pre-paid shipping materials included.

A man taking the IBS-Smart blood test and a woman taking the Trio-Smart breath test

3 - Get Answers

Get test results securely emailed to you within 2-5 business days of the lab receiving your samples that you can share with your healthcare provider.

Patient results displayed on smartphone.

Trusted by Over 100,000 Patients & Physicians

As Seen On

The Doctor's Farmacy
SIBO SOS Podcast
SIBO Made Simple
Revolution Health Radio
Funk'tional Nutrition Podcast
Dr. Ruscio Radio

Not Sure Where To Start?

Use this quick symptom guide to start your gut health journey to feeling better quickly, saving hundreds of dollars on unnecessary and invasive testing, and get that ever valuable peace of mind by diagnosing the root cause of your symptoms.

Select Your Primary Symptom

Trio-Smart: The Comprehensive Breath Test

Best for: Gaseous symptoms like bloating, belching, and flatulence.

  • Tests for all 3 fermentable gases (Hydrogen, Methane, Hydrogen Sulfide).
  • Associated Conditions: SIBO, IMO, and ISO
  • At-home breath collection kit.
Get Trio-Smart

View Full Symptom Guide Chart

Also Consider: IBS-Smart

If you experience bloating accompanied by more frequent diarrhea than constipation, it could be indicative of Post-Infectious IBS. Get quick results by using our easy, at-home blood test, IBS-Smart.

IBS-Smart

Since diarrhea is the hallmark of Post-Infectious IBS, this blood test checks for the anti-CdtB and anti-Vinculin antibodies.

  • Accurate results up to 100% positive predictive value
  • At-home sample collection
  • Fast results within 7 days
Get IBS-Smart

View Full Symptom Guide Chart

Highly Recommended: Trio-Smart: Focus on Hydrogen Sulfide

Diarrhea can also be caused by excessive hydrogen sulfide, one of three fermentable gases in the gut. Associated conditions include Small Intestinal Bacterial Overgrowth (SIBO) and Intestinal Sulfide Overproduction (ISO).

Trio-Smart: Identifies Methane

Best for: Chronic constipation and persistent slow-transit symptoms.

  • Detects methane, the primary gas linked to Intestinal Methanogen Overgrowth (IMO).
  • Associated Conditions: SIBO, IMO
  • At-home breath collection kit.
Get Trio-Smart

View Full Symptom Guide Chart

IBS-Smart: The Post-Infectious Blood Test

Best for: Patients with a history of food poisoning followed by chronic IBS symptoms.

  • Measures antibodies (Anti-CdtB and Anti-Vinculin) caused by food poisoning.
  • Validates a physical cause for your gut symptoms.
  • At-home blood collection kit.
Get IBS-Smart

View Full Symptom Guide Chart

Also Consider: Trio-Smart

Recent studies show that 60% to 70% of IBS patients may also have SIBO1, particularly those with IBS-C or chronic constipation, though it can occur in all IBS types.

"It has changed my life. Once you receive the results, you can move forward and begin your journey to feeling better." —Janice